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Under conventional interpretation, small monomeric or dimeric molecules activate Trks upon binding by inducing receptor dimerization

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Our body naturally produces Glutathione, but due to aging, stress, and environmental toxins, our body's ability to make it decreases over time

This allows CHAC1 to post-translationally regulate protein activity by binding and cleaving specific -glutamyl amino acids ( Although CHAC2 enzymes in Leishmania major were shown to degrade only reduced and not oxidized glutathione, this specificity has yet to be confirmed for CHAC1 ( CHAC2 is both evolutionarily older and structurally distinct from CHAC1

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